Common, Mild, Serious Side Effects of Apriso, and Guidance for Management
Apriso, a brand-name capsule, is often prescribed for maintaining remission in ulcerative colitis, a chronic inflammatory bowel disease. This medication, known as mesalamine, aims to reduce inflammation in the colon with fewer systemic effects compared to older drugs.
While long-term side effects are generally considered rare and mild, it's essential to be aware of potential risks. Kidney function impairment is one concern, requiring periodic monitoring. Liver enzyme abnormalities can also occur, so regular checks are advised.
Rare hypersensitivity reactions, such as rash, fever, or inflammation of other organs like the pancreas or lungs, have been reported. Serious adverse effects are rare but possible. Compared to sulfasalazine, which can have more severe side effects, mesalamine is usually better tolerated.
Hair loss is a possible, albeit rare, side effect of Apriso. If you notice hair loss, it might be worth discussing nutrient deficiencies with your healthcare provider.
Mesalamine-induced acute intolerance syndrome is another rare side effect that can occur. Symptoms include diarrhea, fever, abdominal pain, and bloody diarrhea. Headache and rash can also be symptoms of this syndrome.
It's important to note that Apriso does pass into human breast milk, exposing a breastfed child to the drug. The safety of taking Apriso while breastfeeding is not known.
Alcohol consumption can increase the risk of side effects when taken with Apriso, including headache, nausea, and liver problems.
Common side effects of Apriso include headache, diarrhea, pain in the upper abdomen, nausea, and common cold. Headaches were the most common side effect reported in clinical trials.
If you're pregnant or planning to become pregnant, talk with your doctor before taking Apriso. In animal studies, Apriso didn't appear to harm fetuses, but human studies are not available.
If you stop taking Apriso, your UC symptoms may come back. It's crucial to have regular follow-ups to watch for these side effects and ensure safe long-term management of ulcerative colitis with Apriso.
In summary, while Apriso is generally well-tolerated, it's essential to be aware of potential long-term side effects, including kidney function impairment, liver enzyme changes, and rare hypersensitivity reactions. If you experience any persistent symptoms or abnormalities, discuss them with your healthcare provider.
- Apriso, a mesalamine-based capsule, is often prescribed for maintaining remission in ulcerative colitis, a chronic inflammatory bowel disease.
- This medication aims to reduce inflammation in the colon with fewer systemic effects compared to older drugs.
- While long-term side effects are generally considered rare and mild, it's essential to be aware of potential risks, such as kidney function impairment and liver enzyme abnormalities.
- Rare hypersensitivity reactions, like rash, fever, or inflammation of other organs, have been reported with Apriso use.
- Hair loss is a possible, albeit rare, side effect of Apriso, and it might be worth discussing nutrient deficiencies with your healthcare provider.
- Mesalamine-induced acute intolerance syndrome is another rare side effect, causing symptoms like diarrhea, fever, abdominal pain, and bloody diarrhea.
- Apriso does pass into human breast milk, exposing a breastfed child to the drug, and the safety of taking Apriso while breastfeeding is not known.
- Alcohol consumption can increase the risk of side effects when taken with Apriso, including headache, nausea, and liver problems.
- Common side effects of Apriso include headache, diarrhea, pain in the upper abdomen, nausea, and common cold, with headaches being the most common side effect reported in clinical trials.
- If you're pregnant or planning to become pregnant, talk with your doctor before taking Apriso, as animal studies did not show harm to fetuses, but human studies are not available.
- If you stop taking Apriso, your UC symptoms may come back, and it's crucial to have regular follow-ups to watch for these side effects and ensure safe long-term management of ulcerative colitis with Apriso.
