Cost, effects, applications, dosage details, and additional information about Voranigo
Taking Voranigo for certain brain tumors is the lowdown on this brand-name pill. It's a prescription-only tablet, and sadly, there's no generic alternative to it. Voranigo contains the active ingredient vorasidenib, being a type of targeted cancer therapy that specifically hits isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2, target enzymes found in certain brain tumors[1].
Approved for treating specific situations involving grade 2 astrocytomas and oligodendrogliomas in people twelve and older, this medication fights back against these brain tumors. It's crucial to check for the mutated isocitrate dehydrogenase-1 (IDH1) or isocitrate dehydrogenase-2 (IDH2) genetic markers before initiating therapy. Along with the base article, it's essential to learn about its potential downsides, drug interactions, and alternatives to make an informed decision regarding treatment.
Drug Details
Voranigo belongs to the isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor class of targeted cancer therapies.
- No generic is available for Voranigo
- Requires a prescription for use
- Not classified as a controlled substance
Voranigo Cost and Coupons
Costs for Voranigo may vary, depending on your insurance coverage, location, and the pharmacy you choose. If you need assistance managing your costs or navigating insurance issues, there are programs like ServierONE available for support[2].
Voranigo Side Effects
Mild and serious side effects can potentially arise from Voranigo usage. Knowing what to expect is essential for managing symptoms and ensuring your safety.
Mild side effects:
- Fatigue
- Headache
- Nausea
- Diarrhea
- Constipation
- Reduced appetite
- Muscle or joint pain/stiffness
- COVID-19
- Decreased white blood cell count
- Increased liver enzymes[2]
less than 40 kg (about 88 pounds [lb])
These mild side effects may go away within a few days to a couple of weeks. Seek medical help if they become severe or persist.
Serious side effects:
20 mg once per day
- Liver problems
- Seizures
- Allergic reactions[2]
In severe cases, contact your doctor right away or emergency services (911) if needed.
Voranigo Uses
For certain brain tumors:
40 kg or more
Certain grade 2 astrocytomas and oligodendrogliomas can be treated with Voranigo. It slows down the growth of these tumors when used after partial or complete surgical removal and biopsy confirming the tumor's specific genetic mutation[3].
The medication may also be prescribed for children aged twelve and up[3].
40 mg once per day
Voranigo Dosage
Dosages for adults and children are age- and weight-adjusted. Consult your doctor for the recommended dosage for your situation.
When taking Voranigo:
- Take once per day at any time, ensuring consistency for a stable drug level in your body
- Don't double up missed doses; simply take the next dose at your regular time
- Voranigo can be taken with or without food
- Don't crush, split, or chew Voranigo tablets; swallow whole with water as intended
- Voranigo is intended for long-term treatment[3]
Voranigo Interactions
Avoid combined use with certain medications, such as Cipro, Cyclosporine, Fluvoxamine, Phenytoin, and Rifampin, as well as specific vitamins, herbs, and supplements[3]. Always share medication information with your healthcare providers to avoid potential interactions.
Alcohol intake may not be safe while taking Voranigo due to the shared risk of side effects, such as headache, nausea, diarrhea, and liver issues[3].
Voranigo Alternatives
• ciprofloxacin (Cipro)• cyclosporine (Neoral, others)• fluvoxamine (Luvox)• phenytoin (Dilantin, Phenytek)• rifampin (Rifadin, Rimatane)• hormonal forms of birth control, such as the combined pill, minipill, or patch
Alternative treatments for brain tumors include chemotherapy with PCV combination regimen, Temozolomide, or Radiation therapy[3]. Speak with your doctor about treatment options that suit your unique needs.
Things to Consider
Pregnancy, fertility, and breastfeeding:
Before conceiving, discuss your treatment options with your doctor and follow recommended birth control measures while taking Voranigo[3].
Potential reproductive harm: Voranigo may affect male and female fertility[3].
Nursing mothers are advised against using Voranigo due to a lack of safety data and the potential for adverse effects on nursing infants[3].
Disclaimer: This article is intended for informational purposes only and should not replace the advice of a qualified healthcare professional. Voranigo is a brand-name medication without a therapeutic equivalent generic alternative. Actual costs may vary, and insurance assistance options like ServierONE are available to help manage expenses. It's vital to discuss all medications and potential interactions with healthcare providers before starting treatment. Always consult your doctor regarding questions about cancer treatments, side effects, or medication interactions.
[1] https://www.cancer.net/treatment/treatments-and-side-effects/targeted-therapies/voranib[2] https://www.drugs.com/voranigo.html[3] https://www.medicalnewstoday.com/drugs/voranigo[4] https://www.fda.gov/drugs/information-drug-class/astrocytoma-and-oligodendroglioma-treatment-voranigo#jump-available
- Voranigo is a targeted cancer therapy used for specific brain tumors, particularly grade 2 astrocytomas and oligodendrogliomas, and requires a prescription.
- The active ingredient in Voranigo, vosaritenib, inhibits isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2, enzymes found in certain brain tumors.
- A generic version of Voranigo is not available, making it a brand-name pill.
- It's crucial to check for the mutated isocitrate dehydrogenase-1 (IDH1) or isocitrate dehydrogenase-2 (IDH2) genetic markers before starting Voranigo therapy.
- Potential side effects of Voranigo include fatigue, headache, nausea, diarrhea, constipation, reduced appetite, muscle or joint pain/stiffness, COVID-19, decreased white blood cell count, increased liver enzymes, liver problems, seizures, and allergic reactions.
- Voranigo may interact with certain medications, such as Cipro, Cyclosporine, Fluvoxamine, Phenytoin, and Rifampin, and should not be taken with alcohol.
- Alternative treatments for brain tumors include chemotherapy, such as the PCV combination regimen, Temozolomide, or Radiation therapy. When considering Voranigo, one should also consider other health-and-wellness factors like mental-health, fitness-and-exercise, and nutrition. Discuss all treatment options with your healthcare professional.
