Cost Variations, Potential Adverse Reactions, Applications, Recommended Amounts, and Additional Information Regarding Voranigo
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Hey there! Check out Voranigo, a potent pill for certain brain tumors. This bad boy contains the active ingredient vorasidenib, which is a type of targeted cancer therapy.
The Food and Drug Administration (FDA) has given the green light to use Voranigo to tackle grade 2 astrocytomas and oligodendrogliomas in adults and kids aged 12 and over. Now, let's dive into the details!
Drug specifics
Here's what you need to know about Voranigo:
- Drug class: vorasidenib falls under isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitors, a category of targeted cancer therapy.
- Generic version? Unfortunately, no generic version is available at the moment.
- Prescription required? Yep, you'll need a prescription from your doc to grab some Voranigo.
- Controlled substance? Nope, it's not classified as a controlled substance.
Voranigo: The generic-less mystery
Since Voranigo is a brand-name medication, you won't find a generic variant of this brain tumor slayer. A generic drug is an exact copy of a brand-name medication’s active ingredient but at a possibly lower cost.
Voranigo prices and coupons
Like all medications, the cost of Voranigo can vary. Your insurance, location, and the pharmacy you visit all play a part in the final amount you'll shell out.
If you're feeling the strain on your wallet, assistance programs like ServierONE are available to help make your prescription more affordable. Simply call 800-813-5905 or visit the program website to learn more and check if you qualify for support like a copay card.
Voranigo side effects
Brace yourself, side effects may come your way when taking Voranigo:
- Mild side effects: Fatigue, headache, nausea, diarrhea, constipation, reduced appetite, pain or stiffness in muscle or joints, and even COVID-19. If these side effects become severe or don't ease up, chat with your doc or pharmacist.
- Serious side effects: Call your doctor immediately if you experience liver problems (pain in the upper right abdomen, loss of appetite, severe tiredness, jaundice, or dark urine), seizures, or allergic reactions. Don't forget, you can also report side effects to the FDA via MedWatch or by calling 800-FDA-1088.
Voranigo uses
Voranigo for the right brain tumors
less than 40 kg (about 88 pounds [lb])
Voranigo is FDA approved to treat certain brain tumors called astrocytomas and oligodendrogliomas in adults and kids aged 12 and over.
Specifically, Voranigo targets grade 2 astrocytomas and oligodendrogliomas that have specific genetic mutations (an abnormal change in a gene). Before your doctor prescribes Voranigo, they'll likely take a biopsy to check for these mutations.
Voranigo and the kiddos
20 mg once per day
Voranigo is officially FDA approved for use in kids aged 12 and over to treat astrocytomas and oligodendrogliomas with specific genetic mutations.
However, Voranigo hasn't been studied in kids younger than 12 years old, so its safety and effectiveness in this age group haven't been determined.
Voranigo dosage
Your dosage will be based on factors like your age, weight, and any side effects you experience. Here's a rundown of typical doses based on weight:
- If your weight is under 40 kg (about 88 lbs): 20 mg once a day.
- If your weight is 40 kg or more: 40 mg once a day.
Follow your doctor's instructions for how to take Voranigo and don't crush, split, or chew the tablets.
40 kg or more
Voranigo interactions
Before taking Voranigo, let your doctor and pharmacist know about all the medications, vitamins, supplements, and foods you consume. Voranigo can interact with several other drugs, including ciprofloxacin (Cipro), cyclosporine, fluvoxamine (Luvox), phenytoin (Dilantin, Phenytek), rifampin (Rifadin, Rimatane), and hormonal forms of birth control.
Voranigo and alcohol
40 mg once per day
Alcohol may not be safe to consume while taking Voranigo since it can cause similar side effects, such as headache, nausea, diarrhea, and liver problems. If you're unsure about the safety of drinking alcohol while on Voranigo, ask your doctor or pharmacist.
Alternatives to Voranigo
Other brain tumor treatments are out there for you. If you're interested in finding an alternative to Voranigo, chat with your doctor. They can tell you about other treatments that might work better for you.
Some alternatives include chemotherapy with drugs such as PCV combination regimen (procarbazine, lomustine [CCNU], and vincristine) and temozolomide, and radiation therapy.
Things to consider when taking Voranigo
If you can get pregnant, keep these points in mind:
- Voranigo should not typically be taken during pregnancy and is not proven to be safe for unborn babies.
- If you are planning to get pregnant or could become pregnant, talk to your doctor about birth control options during treatment.
- If you take Voranigo, you should use a nonhormonal form of birth control, such as condoms, while taking the medication and for 3 months after your last dose.
If you have any questions about pregnancy, fertility, birth control, and breastfeeding, talk to your doctor.
Voranigo's gameplan
Voranigo works by blocking the action of abnormal IDH1 and IDH2 enzymes in brain tumor cells. These enzymes are involved in making energy for cells, but when they're mutated, they produce a molecule that helps tumor cells grow. By stopping these enzymes from functioning, Voranigo slows down the growth of brain tumor cells.
Don't forget, Voranigo is meant to be a long-term treatment, so if you and your doctor determine that Voranigo is safe and effective for you, you'll likely take it long-term.
Safe travels on your Voranigo journey, buddy! As always, consult your doctor if you have any questions or concerns.
• ciprofloxacin (Cipro)• cyclosporine (Neoral, others)• fluvoxamine (Luvox)• phenytoin (Dilantin, Phenytek)• rifampin (Rifadin, Rimatane)• hormonal forms of birth control, such as the combined pill, minipill, or patch
- Voranigo, a potent pill for certain brain tumors, is a targeted cancer therapy that contains the active ingredient vorasidenib.
- The Food and Drug Administration (FDA) has approved Voranigo to treat grade 2 astrocytomas and oligodendrogliomas in adults and children aged 12 and over.
- Voranigo falls under isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitors, a category of targeted cancer therapy.
- A generic version of Voranigo is not available at the moment, resulting in a higher cost compared to generic drugs.
- Voranigo can have side effects such as fatigue, headache, nausea, diarrhea, constipation, reduced appetite, pain or stiffness in muscle or joints, and even COVID-19.
- More serious side effects include liver problems, seizures, and allergic reactions, requiring immediate medical attention.
- When taking Voranigo, it is important to avoid alcohol since it can cause similar side effects such as headache, nausea, diarrhea, and liver problems.
- Alternatives to Voranigo for treating brain tumors include chemotherapy with drugs such as PCV combination regimen and temozolomide, and radiation therapy, which should be discussed with a doctor.
