Ibuprofen and its Impact on the Body
Does the commonly used painkiller, Ibuprofen, potentially influence an individual's blood pressure levels?
Ibuprofen, a member of the non-steroidal anti-inflammatory drug (NSAID) family, is widely used for alleviating symptoms such as headaches, muscle pain, fever, or joint inflammation. However, its long-term use can pose potential dangers to cardiovascular health, a risk not limited to older individuals.
NSAIDs, including ibuprofen, naproxen, and diclofenac, work by inhibiting certain enzymes in the body. These enzymes, known as cyclooxygenases, are responsible for the production of prostaglandins, which act as inflammation messengers. By targeting these enzymes, ibuprofen prevents the formation of inflammatory messengers, providing pain relief and anti-inflammatory effects.
Ibuprofen is available in various forms, such as tablets, capsules, creams, and syrups. Adult dosages typically range from 400 mg to prescription strengths of 600 mg and 800 mg for stronger pain or fever. For children, lower-strength preparations are available.
Common Side Effects of Ibuprofen
Although many users are aware of ibuprofen's potential for stomach and intestinal problems, the German Heart Foundation warns of other contraindications. Ibuprofen is not recommended for individuals with:
- known hypersensitivity to ibuprofen
- bleeding or tendency to bleed
- severe liver and/or kidney dysfunction
- allergies to any of the ingredients
- respiratory diseases
- untreated high blood pressure
- severe heart weakness
Likely side effects include headaches, dizziness, fatigue, heartburn, abdominal pain, nausea, vomiting, digestive problems, skin rash, edema, increased risk of stomach ulcers, and gastrointestinal bleeding.
Study Findings: Ibuprofen and Blood Pressure
A 2017 study conducted by the University Hospital Zurich (USZ)Reported an increased risk to heart health from using ibuprofen. The study found that prolonged use, particularly at high doses, significantly increased the risk of heart attack and stroke. According to the Herzmedizin portal, regular use of ibuprofen over one to seven days could potentially double the risk of a heart attack.
In this study, 444 participants, primarily those with osteoarthritis or an increased risk of coronary artery disease, were administered one of three medications:
- Celecoxib, which reduced blood pressure by an average of 0.3 mmHg
- Ibuprofen, which increased blood pressure by 3.7 mmHg
- Naproxen, which increased blood pressure by 1.6 mmHg
Prof. Frank Ruschitzka, deputy director of the Clinic for Cardiology at USZ and the study's leader, stated that "Ibuprofen is clearly not as safe as previously thought."
Paracetamol: An Alternative with Risks
Paracetamol is often viewed as a seemingly harmless alternative to ibuprofen by those experiencing pain or fever. However, a small-scale study by the High Blood Pressure League revealed an increase in blood pressure with Paracetamol use. This increase in blood pressure was observed in individuals with pre-existing high blood pressure. The implications for those without high blood pressure remain unclear, but caution is advised when using Paracetamol.
Although ibuprofen does carry potential side effects, it remains the preferred treatment for many pain conditions. It is often used for coccyx pain or bladder infections, and should be included in travel first aid kits.
Key Points:
- Ibuprofen can raise blood pressure, particularly in those with pre-existing conditions.
- Prolonged use of ibuprofen increases the risk of heart attack, stroke, and kidney/liver strain.
- Paracetamol may also increase blood pressure in individuals with pre-existing high blood pressure.
High blood pressure patients, heart disease patients, those with kidney or liver issues, and those taking blood pressure medications should exercise caution when using ibuprofen for extended periods. Consult a healthcare provider for guidance.
Science reveals that regular use of ibuprofen, a common pain reliever, can have detrimental effects on health-and-wellness. A study by the University Hospital Zurich discovered that prolonged ibuprofen use significantly increases the risk of heart attack and stroke, particularly at high doses. Mental health is also a consideration, as ibuprofen can aggravate symptoms such as headaches and dizziness. To counterbalance these potential issues, it's essential to explore therapies-and-treatments like Paracetamol, which may pose its own risks, particularly in individuals with high blood pressure. Nutrition plays a vital role in maintaining overall health, and it's advisable to consider a balanced diet alongside the use of pain-relieving medications for fitness-and-exercise recovery and mental well-being.
