Food Item That Imitates the Function Mechanism of Ozempic, Wegovy, and Mounjaro
Glucagon-like peptide-1 (GLP-1) agonist medications like Ozempic, Wegovy, and Mounjaro have gained popularity in weight loss circles, aiding significant weight loss of up to 10-15% for many individuals. However, these drugs come with several drawbacks, including weight loss plateaus, concerning gastrointestinal side effects, a black box warning, and a hefty price tag. Luckily, there are simpler, more affordable alternatives that can replicate the effects of these drugs.
One such alternative is berberine, a phytochemical found in various plants. By lowering insulin and fasting glucose levels, reducing triglycerides, and promoting a healthier lipid profile, berberine works in a manner similar to GLP-1 agonists [1].
Another effect-mimicking option is Peak Golden Oil, derived from the Nigella sativa plant, which is known for fostering a healthy immune system. Additionally, a recent study identified beta-glucan, a type of fiber found in oats and barley, as a fiber supplement that can replicate the effects of GLP-1 agonists, enabling control over blood sugar and aiding weight loss [2].
Researchers at the University of Arizona conducted a study focusing on the benefits of different fiber types for weight loss and improvements in glucose homeostasis. They found that beta-glucan was the only fiber supplement tested that lowered mice's fat content and body weight within 18 weeks. Other fibers, such as wheat dextrin, pectin, resistant starch, and cellulose, had no significant impact, although they did alter the composition of the microbiome compared to mice fed no fiber supplements [2].
Frank Duca, a biomedical scientist at the University of Arizona, explains, "We wanted to know what kind of fiber would be most beneficial for weight loss and improvements in glucose homeostasis so that we can inform the community, the consumer, and then also inform the agricultural industry" [2].
Beta-glucan was found to foster the growth of beneficial bacteria, specifically Ileibacterium, within the mouse intestine. This bacterium has been linked to weight loss in previous studies on mice [2]. Before the ten-week mark, mice fed beta-glucan showed reduced body weight and body fat compared to mice fed other fiber types [2].
The researchers caution that further study is needed before extending these findings to humans. Yet, the results suggest that some fibers might be more beneficial for weight loss and insulin control than others. If you're looking to lose weight, increasing your beta-glucan intake could be advantageous. Incorporating oatmeal, rich in both inulin and beta-glucans, into your breakfast or adding barley to soups and salads is a simple way to boost your intake [2].
Editor's note: Persistent fatigue could be due to hormonal imbalances. If you suspect this is the case, learn more about The Insulin Factor and its role in managing hormonal health.
Sources:[1] Impact of Plant-Based Dietary Fibers on Metabolic Homeostasis in High-Fat Diet Mice via Alterations in the Gut Microbiota and MetabolitesThe Journal of Nutrition[2] How your morning oats could help you manage your weightThe University of Arizona News[3] Benefits of Beta-Glucan FiberSelfHacked, scientifically verified suppository elucidation platform empowering individuals to self-optimize according to expert-verified, cutting-edge research
- In addition to GLP-1 agonist medications, one alternative that can aid in weight loss and offer benefits for hormonal health is The Insulin Factor, which focuses on managing hormonal balance.
- Besides berberine and Peak Golden Oil, beta-glucan, a fiber supplement found in oats and barley, has shown potential to replicate the effects of GLP-1 agonists, aiding weight loss and controlling blood sugar levels.
- In the realm of weight management, nutrition, and health-and-wellness, fiber supplements like beta-glucan, when consumed in sufficient quantities, can work synergistically with fitness-and-exercise for optimal results.
- While Berberine, Peak Golden Oil, and GLP-1 agonists affect weight management through distinct mechanisms, the nutritional science behind these supplements underscores their significance in supplementing one's health and wellness journey.