Interactions of Otezla with alcohol, various drugs, and other substances
Otezla, a medication used to treat plaque psoriasis, psoriatic arthritis, mouth ulcers associated with Behcet's disease, and plaque psoriasis in children aged 6 years and older, can interact with certain substances. It's essential to be aware of these interactions to ensure the best possible treatment outcome.
Firstly, Otezla can interact with certain antibiotics, antiseizure drugs, certain cancer drugs, cystic fibrosis drugs, and barbiturate drugs. For instance, specific cancer drugs like mitotane (Lysodren), enzalutamide (Xtandi), and apalutamide (Erleada) may interact with Otezla. Similarly, antiseizure drugs such as phenytoin (Dilantin, Phenytek) and carbamazepine (Carbatrol, Tegretol, others) could potentially affect the effectiveness of Otezla.
It's also worth noting that drinking alcohol could worsen some of Otezla's side effects, such as fatigue, nausea, and headache. If you've had an allergic reaction to Otezla or its ingredients, your doctor will likely not prescribe Otezla.
Regarding interactions with herbs, it's recommended to avoid taking St. John's wort with Otezla, as it may speed up the activity of an enzyme that breaks down Otezla, potentially reducing its effectiveness.
However, when it comes to cannabis or CBD, there are no known direct interactions between Otezla and these substances. Nevertheless, given the potential effects of CBD on physiology, such as lowering blood pressure, fatigue, and changes in metabolism, it's always best to consult your healthcare provider before using cannabis or CBD with Otezla.
Several other factors and substances may interact with Otezla. For example, kidney problems, weight loss, depression, pregnancy or breastfeeding, and allergic reactions to Otezla or its ingredients can affect its use. Additionally, while there are no specific reports of vitamins or food interacting with Otezla, it's always a good idea to discuss any vitamin product or dietary changes with your doctor or pharmacist before taking them with Otezla.
Lastly, there are no known interactions between Otezla and vaccines, lab tests, or specific antibiotics. However, taking Otezla with certain cystic fibrosis drugs, certain cancer drugs, and barbiturate drugs could make Otezla less effective.
In conclusion, while no direct interactions have been identified between Otezla and cannabis or CBD, it's crucial to discuss any cannabis or CBD use with your prescribing doctor. They can monitor you appropriately for any unexpected effects or changes in effectiveness. Always remember, open communication with your healthcare provider is key to managing your treatment effectively.
[1] Source: Medscape Drug Interaction Checker [2] Source: Cannabis and CBD: What You Need to Know About Interactions with Medications
- Otezla, a pharmaceutical used to treat certain medical-conditions like psoriasis, psoriatic arthritis, and arthritis, can interact with several drugs, including antibiotics, antiseizure drugs, cancer drugs, cystic fibrosis drugs, and barbiturate drugs.
- Specific examples of drugs that may interact with Otezla include mitotane, enzalutamide, apalutamide, phenytoin, and carbamazepine.
- It is essential to be aware of these interactions to ensure the best possible treatment outcome, as some interactions could potentially reduce the effectiveness of Otezla.
- Regarding interactions with herbs, it is recommended to avoid St. John's wort when taking Otezla, as it may speed up the activity of an enzyme that breaks down Otezla.
- When it comes to health-and-wellness substances like cannabis or CBD, the interactions with Otezla are less clear, but it is always best to consult your healthcare provider before using these substances while on Otezla.
