New Patent Application Submitted for Innovative Water Testing Technique to Identify Harmful Toxins
UC San Diego's Scripps Oceanography, in collaboration with the University of São Paulo, has developed a revolutionary freshwater monitoring tool for Guanitoxin, a potent neurotoxin produced by cyanobacteria. This tool is set to make a significant impact on public health and freshwater environments.
The Impact on Public Health
Early detection and prevention of harmful substances like Guanitoxin are crucial. With this new tool, communities that rely on freshwater sources for drinking, recreation, or irrigation of food crops can safeguard against exposure to these toxic compounds. By mitigating neurological effects, public health measures can be implemented to reduce the incidence of neurological disorders or other health issues.
The Impact on Freshwater Environments
Monitoring tools, such as this one for Guanitoxin, can help identify areas where toxic compounds are present. This allows for targeted conservation efforts to protect aquatic life and maintain the balance of freshwater ecosystems. Moreover, improved water quality management can be achieved by detecting substances like Guanitoxin, benefiting both human health and biodiversity within freshwater ecosystems.
The commercialization of this new detection method means that Guanitoxin could soon become part of standard toxin monitoring in freshwater environments. The monitoring kits are being offered under the brand Phytoxigene by Diagnostic Technology.
Scripps Oceanography's Role
Scripps Oceanography, one of the world's most important centers for global earth science research and education, is home to a culture of exploration and experimentation. Its scientists work tirelessly to understand and protect the planet, investigating our oceans, Earth, and atmosphere to find solutions to our greatest environmental challenges.
In May 2022, a paper was published establishing the precise functions of all nine enzymes responsible for Guanitoxin biosynthesis. This significant breakthrough paves the way for further advancements in understanding and combating this toxic compound.
Scripps operates a fleet of four oceanographic research vessels and is also home to Birch Aquarium at Scripps, a public exploration center that welcomes 500,000 visitors each year.
Recent Developments
The technology for Guanitoxin detection has been licensed to Phytoxigene, Inc., and has been incorporated into an existing assay for the detection of another HAB toxin called anatoxin. This integration promises to enhance the efficiency and accuracy of toxic compound detection in freshwater environments.
In 2014, Toledo, Ohio issued a "do not drink" advisory due to a Harmful Algal Bloom (HAB) outbreak. Such events underscore the importance of tools like the one developed by Scripps and the University of São Paulo. Essential healthcare treatments such as dialysis and surgery had to be halted in Toledo due to the HAB outbreak, highlighting the potential severity of these incidents.
People who swim in waters with HABs have suffered adverse health effects, ranging from vomiting to neurological impairment. With the development and commercialization of this new tool, public health officials now have a valuable resource to help protect communities from the dangers of Guanitoxin and other harmful toxins.
The University of California San Diego embraces a culture of exploration and experimentation. Established in 1960, it is one of the top 15 research universities in the world, driving innovation and change to advance society, propel economic growth, and make our world a better place.
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