Prolonged seating linked to shrinkage of the brain and increased risk of mental decline, findings suggest. - Prolonged sitting contributes to brain shrinkage and increases the risk of dementia, according to new research.
Prolonged Sitting Linked to declines in Cognitive Function and Brain Shrinkage
Prolonged periods of inactivity, particularly sitting for extended hours, have been found to adversely affect brain health, cognitive function, and increase the risk of dementia. The following are key findings from a study on oxidative stress and its impact on brain health.
Cognitive performance and brain health
The study reveals that prolonged sedentary behavior is linked to cognitive decline, affecting memory and other cognitive functions, even in physically active individuals [1][2]. Furthermore, research indicates that sitting for long hours can lead to brain shrinkage, particularly in regions susceptible to Alzheimer's disease, such as the hippocampus [1][2].
Moreover, reduced blood flow to the brain resulting from prolonged sitting decreases the delivery of oxygen and nutrients essential for maintaining brain health [2][5].
Risk of Dementia
Increased sedentary behavior has been associated with a higher risk of Alzheimer's disease, particularly among individuals carrying the APOE-e4 gene, a major genetic risk factor for Alzheimer's [1][4]. Prolonged sitting also contributes to neurodegeneration by exacerbating vascular dysfunction and inflammation in the brain [3].
Mitigation Strategies
While exercise is beneficial, it does not fully offset the effects of prolonged sitting. Incorporating more movement into daily routines, such as taking regular breaks, can help mitigate the risks associated with sedentary behavior [1][5].
Additionally, strategies like "active sitting," which involve incorporating movement during sitting hours, can help maintain blood flow and reduce the negative impacts of prolonged sitting [5].
In conclusion, reducing sedentary time and promoting an active lifestyle are vital for preserving brain health, safeguarding cognitive function, and lowering the risk of dementia.
The community should implement policies that encourage regular breaks and active sitting to mitigate the risks associated with prolonged sedentary behavior, as studies show that too much sitting can lead to cognitive decline and brain shrinkage. Moreover, to emphasize holistic health, vocational training programs could integrate science-based health-and-wellness courses, including mental-health modules and therapies-and-treatments focusing on stress management and brain health, to further support individuals in maintaining optimal cognitive performance and overall wellness.
