Scientists Reveal Boundaries' Active Role in Network Deformation
Scientists have discovered that the geometry of boundaries actively directs the deformation of networks in reconstituted systems. This research, led by experts like Ellen M. Munro, offers insights into the mechanical behaviour of living cells and tissues, and provides a basis for designing materials with tailored mechanical properties.
The study found that the strength of contraction remains consistent across different geometries. However, the size and shape of the network significantly influence the overall domain of activity. Boundaries, previously thought of as passive constraints, are now understood to be active regulators of network organisation. In systems built from microtubules and motor proteins, the geometry of boundaries dictates the contraction of networks. The extent of boundary deformation increases with higher stress and decreases with greater stiffness. Researchers observed local fluctuations along the boundary that contribute to overall deformation. The interplay of internal stresses, network geometry, and local fluctuations governs boundary deformation in active networks.
This research establishes a framework for understanding the dynamics of active boundaries. It demonstrates the crucial role of boundary geometry in controlling network deformation. This discovery could pave the way for designing materials with specific mechanical properties, mimicking the behaviour of living cells and tissues.
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