Side Effects of Orserdu: Detailing Their Impact and Management Strategies
Orserdu, a selective estrogen receptor degraders (SERD) drug, is used in the treatment of certain types of breast cancer. While it is effective in managing the disease, it is essential to be aware of its potential side effects.
Common side effects of Orserdu include fatigue, muscle and joint pain, increased cholesterol levels, decreased hemoglobin levels, nausea, and mild allergic reactions. However, less common or milder side effects may also occur, such as:
- Diarrhea
- Constipation
- Headache
- Heartburn
- Hot flushes
- Indigestion
- Stomach discomfort or pain
- Vomiting
- Decreased appetite
- Unusual tiredness or weakness beyond general fatigue
These side effects usually do not require medical attention but should be reported if persistent or bothersome.
In addition to the above, some SERDs and cancer therapies may cause severe cutaneous adverse reactions (SCARs), swelling (edema) in the face, eyes, extremities, or abdomen, and eye problems such as keratitis or retinal pigment epithelial detachment. These are rare but serious events that require prompt medical attention if vision changes or eye symptoms occur.
Serious side effects of Orserdu include increased creatinine level, increased liver enzyme levels, and severe allergic reactions. If you experience symptoms of an allergic reaction, such as skin rash, itching, flushing, swelling, or difficulty breathing, seek immediate medical attention.
Orserdu may also affect your liver, so if you have a liver condition such as hepatitis, inform your doctor before beginning treatment. It is not clear if Orserdu can cause long-term side effects.
Comparatively, some side effects of Orserdu are the same as those of Faslodex, such as fatigue, joint pain, decreased appetite, diarrhea, increased liver enzyme levels, nausea, and hot flashes. However, Faslodex may cause side effects not common with Orserdu, such as hair loss, back pain, and bleeding and bruising easily.
If you are pregnant or breastfeeding, Orserdu is not considered safe for your pregnancy or your child. Alcohol consumption may interact with Orserdu, so consult your pharmacist or doctor if you have questions about how much alcohol is safe to drink while taking Orserdu.
For mild symptoms, such as nausea, taking Orserdu with food may help. Strategies to reduce hot flashes include maintaining a nutritious diet, regular exercise, stress management, avoiding alcohol and caffeine before bedtime, avoiding smoking and secondhand smoke, limiting spicy foods, maintaining a comfortable body temperature, and wearing loose-fitting cotton clothing.
Before starting Orserdu treatment, discuss any medical conditions or factors that may affect your health with your doctor. It is crucial to monitor for the side effects mentioned and inform your healthcare provider if they occur. If you have any questions or concerns about Orserdu and its side effects, talk with your doctor or pharmacist.
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