UK Blood Safety Body Probes Potential Transfusion-Linked Brain Disease
Professor James Neuberger, chair of the UK's SaBTO (Scientific Advisory Committee of the Blood Transfusion Services), has raised concerns about the potential transmission of iatrogenic cerebral amyloid angiopathy (ICAA) through blood transfusions. SaBTO is currently investigating this issue, with its findings to be considered by ministers.
US researchers have discovered a link between blood transfusions and ICAA in two patients who received transfusions as children and were later diagnosed with the disease at ages 47 and 57. ICAA is a brain disease caused by the buildup of amyloid protein in the blood vessels, making them fragile and prone to bleeding. While typically affecting people in their 70s and 80s, ICAA can also appear much earlier, especially after medical procedures.
NHS Blood and Transplant has acknowledged the potential risks, stating that all blood transfusions carry some level of risk. They follow the advice of independent expert committees, such as SaBTO, to ensure the safety of the blood supply.
A senior government adviser on blood transfusion safety has expressed concern about the possibility of ICAA being passed from donor to patient. SaBTO's investigation into this matter is ongoing, and its recommendations will be considered by ministers to ensure the safety of blood transfusions.
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